Urine Diagnostics / Urine Test Strips / Portfolio Urine Test Strips / Protein


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Test principle
The test pad changes from yellow to green.
Sensitivity
A colour reaction is observed from 15 mg/dl (0.15 g/l) albumin.
Specifity
The test strip reacts particularly sensitively to albumin.
Other proteins (such as globulins, Bence-Jones proteins, peptones, mucoproteids, albumoses) show less sensitivity.
Sources of errors

False-positive results can occur: 

  • in highly alkaline urines (pH>9) with high specific gravity,
  • following infusions with blood substitutes (polyvinylpyrrolidone),
  • in patients treated with pharmaceutics containing quinine
  • if the specimen container is contaminated by disinfectants with quarternary ammonium groups.
Clinical significance
The urine of most healthy people contains only traces of protein. Values up to 30 mg/dl (0.3 g/l) in morning urine are considered as physiological.

Pathological proteinurias generally begin at >30mg/dl. Proteinurias are the most important laboratory diagnostic symptom of kidney diseases and occur as the result of glomerular or tubular damage. Proteinuria is not necessarily present in cases of nephropathy. The causes of persistently increased protein elimination should therefore be determined using differentiated diagnostics. It is recommended to use the first morning urine for testing on protein.

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